Associate Professor

Department: CSD
Telephone: 928-523-8142
Email: Oneil.Guthrie@nau.edu

O’neil W. Guthrie, Ph.D., CCC-A
Associate Professor
Post-doc, Duke University, USA
PhD, University of Pittsburgh, USA
MS, State University of New York College at Fredonia, USA
BS, State University of New York College at Geneseo, USA

Courses taught

CSD 376 Hearing Science
BIO 485: Undergraduate Research
CSD 508:  Neurobiology
BIO 685: Graduate Research
BIO 685: Graduate Research – Gross Human Anatomy
BIO 697: Independent Study
BIO 699: Graduate Thesis

Research

Cell and Molecular Pathology

Press release about Dr. Guthrie’s research, National Public Radio (NPR):

Airplane Noise May Cause Health Problems – NPR

Brain Food: Strengthening Cells To Prevent Or Reverse Hearing Loss – NPR

Additional information about Dr. Guthrie’s research:

Ototoxicity: A Problem of Interacting Variables – AudiologyOnline

ASHA Voices: The Limits of Our Genes – The ASHA Leader

Gene Therapy: Current Promises and Future Challenges – ASHA On Demand Webinar

The Impact Of Jet Fuel and Noise on the Nervous System – YouTube

Role of DNA Repair in the Cochlea, presented in partnership with the American Auditory Society – AudiologyOnline

Areas of interest

Dr. O’neil W. Guthrie received his B.S. and M.S. degrees from the State University of New York campuses at Geneseo and Fredonia.  He completed research training in molecular biology and audiology at the University of Pittsburgh where he earned a Ph.D. He then completed postdoctoral training in molecular genetics at Duke University where he was awarded the Hargett Cell Biology Fellowship.  In addition to his research credentials, he is also a licensed clinical audiologist with over 15 years of diagnostic and rehabilitation experiences. His basic science research program is focused on revealing molecular mechanisms that regulate the integrity of active genes and the engineering of biomedical approaches to enhance the capacity of cells to protect their DNA. To this end, Dr. Guthrie’s research group employs a range of genetic, epigenetic, molecular and pharmacologic strategies to regulate cellular DNA repair capacity. The research from this work has led to patented and unpatented molecular constructs that could affect clinical outcomes. In addition to his basic science research program, Dr. Guthrie is also interested in translational research that improves clinical and epidemiology outcomes. His research on the interaction between jet-propulsion fuel and background noise exposure has revealed that such combined exposures can disrupt brain functions without peripheral nervous system impairment or hearing loss. This work challenges federal, state and local regulators to consider auditory brain dysfunctions in regulations that govern civilian and military work exposures. His research has been generously supported by the National Institutes of Health (NIH), Department of Defense (DoD/Air Force) and the Veterans Administration. Dr. Guthrie is the Principal Investigator for the Cell and Molecular Pathology Laboratory (CMPL) in Wettaw biochemistry.