Wettaw (Bldg. 88)
115 W. Dupont St.
BDL mailing address
617 S. Beaver St.
Bldg 21, Rm. 227
Flagstaff, AZ 86011
PO Box 5640
Flagstaff, AZ 86011-5640
Bioengineering Devices Lab (BDL)
An NAU Mechanical Engineering Lab
The BDL provides opportunities to Ph.D., Masters, and undergraduate students interested in neurovascular devices such as new microcatheter designs, ischemic stroke systems, and innovative embolic agents for aneurysms (improving on coils, flow diverters, liquid embolics, etc). The lab conducts extensive in vitro cerebrovascular flow model development and simulates patient anatomies with innovative 3D-printed tissue-like biomaterials.
The lab is affiliated with Barrow Neurological Institute (BNI – Phoenix, AZ) and Northern Arizona Healthcare to collaborate on translational medical device research. Undergraduate and graduate researchers from the BDL actively collaborate with small start-ups and large-industry leaders in medical device development, published in internationally renowned journals, and attend annual conferences to present their work. Conferences regularly attended include BMES – Biomedical Engineering Society, Surfaces – Surfaces in Biomaterials Foundation, and SNIS – Society of NeuroInterventional Surgery.
BDL Research Accordion Closed
The BDL focuses on industry-driven research programs as well as government-funded basic research. Among the lab’s extensive research efforts, it provides engineering students an opportunity to assist with research and year-long capstone projects where student groups design prototype systems for industrial clients. Our goal is to create a new generation of biomedical engineering students with the research expertise to become bioengineering and biomedical engineering industry leaders.
Current research includes:
BDL Facility Accordion Closed
The BDL is one of several labs affiliated with the Bioengineering Program that share lab equipment and space in the Wettaw building.
The lab facility:
- The lab has 600 sq. ft. of space with 4 sinks (DI and Milli-Q water), 2 fume hoods, 5 large lab benches/bays, working space, and computer access for up to 12 researchers
- A bench dedicated to the HR2 hybrid rheometer for temperature-controlled rheology and DMA testing:
- Shear and elastic modulus testing
- Tension testing (up to 500º C)
- Tribo-rheometry for wear resistance
- Optics plate – camera for real-time imaging during mechanical testing
- Pull friction testing for vascular devices
- Magneto-rheology for smart materials and nanoparticle testing
- A bench dedicated to formulating biomaterials (polymer constructs, hydrogels, and shape memory polymers – SMPs)
- A bench houses the in vitro vessel model for vascular modeling and endovascular surgical procedure simulations
- ViVitro Superpump: cardiovascular and neurovascular flow modeling
- Superpump heat exchanger and flow reservoir: body temperature flow
- Real-time blood pressure and flow measurement (in-line pressure transducers)
- 16+ channels of pressure, flow, and temperature monitoring (Ni-DAQ and LabView data acquisition)
- Real-time particle detection (Laser Diode, Controller, and CCD camera system)
- A bench that houses surgical supplies and medical devices
- Benches include computer stations (Microsoft Suite, MATLAB, LabVIEW, SolidWorks, Photoshop, DICOM, etc.)
- Sterrad NX plasma sterilizer for low temperature, hydrogen peroxide sterilization for heat-sensitive microcatheter-based systems, sensitive equipment and electronics, and in vitro model supplies
- Stratasys ObJet260 Connex3 3D-printer
- Multi-material and multi-layering 3D-printer (compatible with over 1000 materials)
- PolyJet technology (hot-swappable multiple material layering, UV-cured) to create research prototypes, human tissue-like models, and research components
- Variety of material properties: soft to flexible, transparent to multi-color, and standard use or biocompatible (implantable) applications
- Layer multiple materials on the same build and time (3 nozzles for 3 different materials at one time)
- 16-micron layers to create highly-specific finalized research-grade prototypes, realistic vessel models, implants, and precise components
- Portable manufacturing cleanroom
- ISO Class 7 sterilizable manufacturing cleanroom (6’ x 8’)
- ISO Class 5 sterilizable product protection cabinet (PPC – 2’ x 4’)
Additional BDL lab resources Accordion Closed
- High-performance computing cluster (HPC) Monsoon and multiple computer labs with specialty software – can be networked to the lab (NAU)
- C-Arm Fluoroscope – digital image transfer (DICOM) to the BDL (Biological Sciences Annex)
- MakerLab (Cline Library) and RAPIDLab (Mechanical Engineering) 3D-printing facilities
- SEM, TEM, confocal, atomic force, light microscope imaging and histology facilities (Imaging and Histology Core Facility)
- Machine shop and CNC lab (Mechanical Engineering)
- Sterile laminar flow hood and cGMP cleanroom facilities (NAU and Moonshot AZ incubator facilities)
- Neurosurgery research facilities (surgical, fluoro, CT, MRI – Barrow Neurological Institute)
- Surgical supplies and device sterilization (Northern Arizona Healthcare)
- Refrigerators, freezers (up to -80 ºC), scales, centrifuge, incubator, tissue culture hood, spectrophotometer, holography, etc.