FluQuant: a Novel Quantitative Real-Time PCR Assay for Quantifying Influenza Viral Load
Description
The technology is a quantitative real-time polymerase chain reaction (RT-PCR) assay, quantifying influenza viral load and detecting influenza virus variants that are resistant to antiviral drugs. The assay provides a highly sensitive and specific set of allele-specific PCR assays, characterizing the frequency of mutation for single-nucleotide polymorphism (SNP) components in influenza virus mixtures across a wide range of DNA concentrations.
Additional information
Patent number and inventor
9,238,844
Paul Keim, David Engelthaler, Elizabeth Driebe, and Cindy Liu.
Potential applications
Clinical applications to treat influenza.
Benefits and advantages
Based on validation studies, the assay is highly sensitive and specific. The technology is easily translatable for clinical and public health diagnosis use.
Case number and licensing status
2009-010
This invention is available for licensing.