Instructional Leadership, emphasis: K-12 School Leadership (MEd)
Molecular structure and liquids used in research labs
  1. NAU
  2. Research
  3. Innovations
  4. Available technologies
  5. Biomedical innovations
  6. Methods, Kits, and Compositions Useful in the Detection of MRSA

Methods, Kits, and Compositions Useful in the Detection of MRSA

Description

The invention provides multiplex assays, methods, and kits to detect and confirm the presence of methicillin-resistant Staphylococcus aureus (MRSA), as well as variants. The variants include methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant coagulase-negative Staphylococcus (MRCNS), and methicillin-resistance Staphylococcusepidermidis (MRSE). Using real-time polymerase chain reaction (RT-PCR), oligonucleotides are used as primers and probes for the presence or absence of the target(s).

Additional information

Patent number and inventor

US 10,100,368

Elizabeth Driebe, David Engelthaler, Jolene Bowers, and Paul Keim.

Potential applications

Clinical applications for hospital-acquired or community-associated infections.

Benefits and advantages

The invention comprises assays that identify and differentiate MRSA, MSSA, MRSE, MSSE, MRCNS, and MSCNS in a sample with high specificity and selectivity. With a high level of accuracy, the invention rapidly identifies MRSA colonization among patients and healthcare workers. Current technologies, such as culturing, are time-consuming. Along with colonization screening, the assay can be used for infection diagnosis.

Case number and licensing status

2010-019

This invention is available for licensing.