Compositions and Methods for Augmenting the Nasal Microbiome
Description
The invention consists of methods to strengthen the nasal microbiome with probiotics, reducing colonization of pathogenic organisms such as methicillin-resistant Staphylococcus aureus (MRSA) in the anterior nares and nasal cavity. In some cases, the method would include the use of a pharmaceutical agent with a probiotic. The probiotics include Dolosigranulum and Simonsiella species.
Additional information
Patent number and inventor
15/568,793
Cindy Liu and Lance Price.
Potential applications
Clinical application to treat Staphylococcus aureus colonization.
Benefits and advantages
There is a critical need for alternative Staphylococcus aureus treatment. The decolonization strategy provides greater long-term success, without selecting for multi-drug-resistant Staphylococcus aureus strains or disrupting the natural nasal microbiome. This method can be used to control, treat, reduce, eliminate, and/or prevent the growth of organisms that negatively impact the health of patients.
Case number and licensing status
2015-026
This invention is available for licensing.