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  6. Diagnostic Tool for Healthcare Surveillance and Antimicrobial Resistance Monitoring of Klebsiella pneumoniae

Diagnostic Tool for Healthcare Surveillance and Antimicrobial Resistance Monitoring of Klebsiella pneumoniae

Description

The technology is a screening tool that detects Klebsiella species and identifies clinically important strains and characteristics using highly multiplexed amplicon sequencing without a live culturing step. The amplicon sequencing tool can be used to detect Klebsiella pneumoniae species, as well as clonal group identification, antimicrobial resistance, and virulence profiling.

Additional information

Patent number and inventor

16/083,860

Jolene R. Bowers, Darrin Lemmer, Jason W. Sahl, Talima Pearson, Elizabeth M. Driebe, David M. Engelthaler, and Paul Keim.

Potential applications

Clinical applications for healthcare-acquired infections.

Benefits and advantages

Using the amplicon sequencing tool, patients could be screened for Klebsiella pneumoniae carriage. The specimen can be collected from urine, wound swabs and tissue, fecal, and respiratory. In turn, a healthcare facility could assess risk of infection and outbreak potential.

Case number and licensing status

2016-033

This invention is available for licensing.