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  6. FluQuant: a Novel Quantitative Real-Time PCR Assay for Quantifying Influenza Viral Load

FluQuant: a Novel Quantitative Real-Time PCR Assay for Quantifying Influenza Viral Load

Description

The technology is a quantitative real-time polymerase chain reaction (RT-PCR) assay, quantifying influenza viral load and detecting influenza virus variants that are resistant to antiviral drugs. The assay provides a highly sensitive and specific set of allele-specific PCR assays, characterizing the frequency of mutation for single-nucleotide polymorphism (SNP) components in influenza virus mixtures across a wide range of DNA concentrations.

Additional information

Patent number and inventor

9,238,844

Paul Keim, David Engelthaler, Elizabeth Driebe, and Cindy Liu.

Potential applications

Clinical applications to treat influenza.

Benefits and advantages

Based on validation studies, the assay is highly sensitive and specific. The technology is easily translatable for clinical and public health diagnosis use.

Case number and licensing status

2009-010

This invention is available for licensing.