Instructional Leadership, emphasis: K-12 School Leadership (MEd)
Molecular structure and liquids used in research labs
  1. NAU
  2. Research
  3. Innovations
  4. Available technologies
  5. Biomedical innovations
  6. Compositions and Methods for Detection and Treatment of Coronavirus Infection

Compositions and Methods for Detection and Treatment of Coronavirus Infection

Description

SARS-CoV-2 is a single-stranded RNA virus that has caused morbidity, mortality, and economic disruption on a global scale. The present method is for diagnosing, prognosing, or monitoring the treatment of coronavirus infection in a subject through highly multiplexed peptide-based serological assays in which libraries of peptide baits—each covalently coupled to a DNA barcode—are synthesized from high-complexity DNA pools using a simple and fully in-vitro approach.

Additional Information

Patent number and inventor

Patent pending

Jason Ladner and John Altin.

Potential applications

High-resolution coronavirus detection.

Benefits and advantages

This method demonstrates accurate detection of SARS-CoV-2 exposure and reveals multiple immunodominant antibody epitopes, including at least one in which antibody responses cross-react between SARS-CoV-2 and an endemic human CoV.

Case number and licensing status

2021-008

This invention is available for licensing.