Jason A. Wilder
Office: bldg.21 room 229
- human evolution
- PhD: Princeton University, Ecology &
Evolutionary Biology, 2002
- BA: Williams College, 1997
I am broadly interested in evolutionary
genetics, particularly in understanding the forces that shape patterns of genetic
variability in nature.
Current NSF- and NIH-supported research
in my laboratory focuses on understanding the history of human genes that
confer resistance to malaria and the influence of variation in microRNA
pathways on cancer susceptibility and progression.
Stump, A.D., S.E. Jablonski, L. Bouton
and J.A. Wilder. In press. Distribution and mechanism of α-amanitin tolerance
in mycophagous Drosophila (Diptera: Drosophilidae). Environmental Entomology.
Wilder, J.A. 2010. Molecular evolution of
glycophorins. Encyclopedia of Life Sciences, DOI:
Wilder, J.A. 2010. Do grandmothers who
play favorites sow seeds of genomic conflict? Bioessays, 32(6):457-460.
Wilder, J.A., E.K. Hewett, M.E. Gansner.
2009. Molecular evolution of GYPC: Evidence for recent structural innovation
and positive selection in humans. Molecular Biology and Evolution,
Wilder, J.A., J. Stone, E. Preston, L.
Finn, H. Ratcliffe and H. Sudoyo. 2009. Molecular population genetics of SLC4A1
and Southeast Asian Ovalocytosis. Journal of Human Genetics, 54(3):182-187.
Brown, B.T., A. Woerner and J.A. Wilder.
2007. Ascertainment bias and the pattern of nucleotide diversity at the human
ALDH2 locus in a Japanese population. Journal of Molecular Evolution,
Wilder, J.A., Z. Mobasher and M.F.
Hammer. 2004. Genetic evidence for unequal effective population sizes of human
females and males. Molecular Biology and Evolution, 21(11):2047-2057.
Wilder, J.A., S. Kingan, Z. Mobasher, M.
Metni Pilkington and M. F. Hammer. 2004. Global patterns of human mitochondrial
DNA and Y-chromosome structure are not influenced by higher migration rates of
females versus males. Nature Genetics, 36(10):1122-1125.
Wilder, J.A. and H. Hollocher. 2001. Mobile elements and the genesis of
microsatellites in Dipterans. Molecular
Biology and Evolution, 18(3):384-392